The following is a list of drugs known to interact with medical marijuana:

Sedative Medications (Barbiturates):

Interaction Rating: Major

Do not take this combination as sedatives and medical marijuana both cause sleepiness and taking these together might cause too much sleepiness

Sedative Medications (CNS Depressants)

Interaction Rating: Major

Do not take this combination as sedatives and medical marijuana both cause sleepiness and taking these together might cause too much sleepiness.

Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal) and zolpidem (Ambien)

Theophylline

Interaction Rating: Major

Do not take this combination as medical marijuana might decrease the effects of theophylline

Disulfiram (Antabuse)

Interaction Rating: Moderate

Be cautious with this combination as Disulfiram (Antabuse) might interact with medical marijuana and can cause agitation, trouble sleeping, and irritability (speak with your healthcare provider)

Fluoxetine (Prozac)

Interaction Rating: Moderate

Be cautious with this combination as fluoxetine (prozac) might interact with medical marijuana and can cause symptoms of hypomania including irritation, nervousness, jittery feeling and excitability (speak with your healthcare provider)

Warfarin (Coumadin)

Interaction Rating: Minor

Be cautious with this combination as warfarin (Coumadin) might interact with medical marijuana and can cause increased bruising and bleeding (speak with your healthcare provider)

Alcohol

Interaction Rating: Major

Medical marijuana intensifies the effects of alcohol causing loss of coordination, intense hangovers and memory loss. Medical marijuana is an anti-emetic and, thus, inhibits vomiting, a sign of alcohol poisoning.